Fig. 2
From: A meta-analysis of genome-wide association studies identifies multiple longevity genes
Study-specific results for the genetic variants in APOE and GPR78. Forest plots for the ApoE ε4 (a) and ε2 (b) variants and rs7676745 (c) based on the results from the 90th percentile versus all controls analysis. The size of the boxes represents the sample size of the cohort. We had no data available for ApoE ε4 in LLFS and for rs7676745 in DKLS, GEHA Italy, GEHA Danish, LLS (combined with GEHA Dutch), Longevity, and Newcastle 85 + . The data for ApoE ε2 in FHS was based on imputation using the Haplotype Reference Consortium reference panel due to the low-imputation quality of this variant when using the 1000 Genomes reference panel
