Fig. 6 | Nature Communications

Fig. 6

From: Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

Fig. 6

Co-localization of associations signals for urinary albumin-to-creatinine ratio (UACR) and gene expression in kidney tissues. The plot shows the nine genes for which there is a high likelihood (posterior probability ≥ 80%) of a shared causal signal for gene expression in at least one of three kidney tissues and UACR. The loci are colored-coded and shown on the y-axis with the closest gene next to the index SNP. Co-localization with gene expression across all tissues (x-axis) is shown as dots, where the size of the dots (implying that eQTL data were available) corresponds to the posterior probability of the co-localization. The change in UACR is color-coded relative to the change in gene expression, or gray in case of a posterior probability < 80%

Back to article page