Fig. 5
From: Brain-targeted drug delivery by manipulating protein corona functions
Biodistribution of sLip and SP-sLip in intracranial glioma. DiI-labeled sLip (sLip/DiI) and SP-sLip (SP-sLip/DiI) were injected via tail vein of nude mice bearing intracranial glioma (at day 16 after implantation). Mouse brains were dissected and sectioned at 4 h after administration. Brain slices were stained with anti-CD31 antibody (green) and biodistribution of liposomes (red) in normal brain tissues (labeled with Brain) and glioma region (labeled with Glioma) were observed by confocal laser scanning microscopy and quantified by Image Pro. Scale bar = 20 μm. Data are means ± SD (n = 3). ***p < 0.001 by student’s t-test
