Fig. 8
High reliability emerges near a critical EI-balance. a1–3 Raster plot of spike times of the same three example neurons as in Fig. 6d, during 30 independent trials of evoked activity, for three different extracellular calcium concentrations ([Ca2+]o = 1.15, 1.25, 1.35 mM). b Population firing rates for all 30 trials for eight different extracellular calcium concentrations. Loss of stimulus discriminatory power away from [Ca2+]o = 1.25 mM as observed by Markram et al.17. c Mean reliability of 2024 pyramidal neurons from layers 4, 5, and 6 during the evoked response vs. extracellular calcium concentration (mean of 30 trials ± 95% confidence interval). d Total population firing rates for excitatory and inhibitory subpopulations in the whole microcircuit during the evoked response
