Table 2 Demographic and Clinical Characteristics: Post RAS Inhibitors

From: Perioperative use of renin-angiotensin system inhibitors and outcomes in patients undergoing cardiac surgery

Ā 

Unadjusted

Inverse probability weighted adjusted

Matched

Data

Ā 

PostRASi (n = 2831)

No-PostRASiI (n = 5299)

p-value

PostRASi (n = 2831)

No-PostRASi (n = 5299)

p-value

PostRASi (n = 2673)

No-PostRASi (n = 2673)

p-value

Age

65.8 ± 11.9

64.7 ± 13.2

0.0004

65.2 ± 20.5

65.1 ± 15.4

0.57

65.7 ± 12

65.8 ± 12.3

0.86

Male

68.4

68.6

0.82

68.7

68.5

0.63

68.4

68.4

0.98

BMI

29.1 ± 6.2

28.8 ± 6.2

0.09

28.9 ± 10.2

28.4 ± 7.5

0.64

29.1 ± 6.2

29.0 ± 6.2

0.61

Diabetes

37.8

29.5

<0.0001

32.7

32.5

0.64

36.2

35.9

0.80

Smoker

38.7

41.3

0.02

39.8

40.3

0.67

39.5

39.7

0.85

Hypertension

83.7

73.9

<0.0001

78.2

78.5

0.42

83.0

83.7

0.49

Cerebrovascular disease

16.8

16.0

0.34

16.1

16.7

0.53

17.0

16.3

0.53

Peripheral arterial disease

13.1

11.6

0.06

12.1

12.3

0.75

12.8

11.9

0.30

Chronic lung disease

18.5

19.5

0.30

19.40

19.0

0.82

18.8

18.7

0.94

Family history CAD

39.1

39.5

0.68

39.0

38.8

0.61

39.3

40.3

0.78

Angina

39.3

34.1

<0.0001

35.1

35.8

0.72

38.5

38.8

0.78

Congestive heart failure

32.3

27.7

0.0001

30.4

30.5

0.86

31.3

30.7

0.62

Previous MI

36.5

30.2

<0.0001

32.1

33.0

0.81

35.4

35.8

0.75

Discharge beta blockers

83.1

82.1

0.07

83.1

82.9

0.32

83.2

83.9

0.61

Discharge aspirin

85.7

84.2

0.03

85.7

85.8

0.69

86.8

85.1

0.25

Discharge lipid lowering

81.0

79.5

0.07

80.3

80.1

0.46

81.9

89.7

0.74

Discharge warfarin

24.5

22.8

0.07

24.0

23.5

0.35

24.1

22.0

0.15

Urgent

53.9

49.3

0.001

51.9

50.7

0.61

52.8

53.1

0.83

CABG

58.5

54.6

0.001

56.2

55.9

0.36

58.0

59.1

0.42

Valve

25.6

27.1

0.13

26.2

26.7

0.59

25.9

25.4

0.68

Pre RAS inhibitor

56.9

34.7

<0.0001

42.9

42.2

0.87

54.6

54.1

0.70

  1. C-index = 0.66, values are mean ± SD or %. p-values are obtained via analyses using Pearson chi-square test or Wilcoxon rank-sum test (unadjusted) and then IPW or PSM (adjusted)
  2. BMI body mass index, MI myocardial infarction, CAD coronary artery disease