Fig. 1

Natural killer (NK) cells are robustly activated during the acute phase of dengue virus (DENV) infection. a Representative staining for CD69 and Ki67 expression on NK cells from one representative patient during the acute, post-febrile, and convalescent phase of DENV infection, and one healthy control. Summary of data showing b Ki67, c CD69 (acute, n = 31; post -febrile, n = 29; convalescent, n = 29; healthy control, n = 26), and d CD38 (acute, n = 10; post -febrile, n = 9; convalescent, n = 10; healthy control, n = 13) expression on CD56^bright and CD56^dim NK cells shown as median fluorescence intensity (MFI), respectively. e, f Summary of data on e Ki67 and f CD69 expression on CD56^bright as well as CD56^dim NK cell subsets, respectively. The CD56^dim NK cells are stratified by differential expression of NKG2A and CD57. NK cells from DENV-infected patients at the acute (n = 25) and convalescent (n = 23) phases of infection. Statistical differences were tested using one-way analysis of variance (ANOVA) and Kruskal–Wallis test followed by Tukey’s multiple comparisons test or Dunn’s multiple comparisons test, respectively. Bars represent mean, *p < 0.05, **p < 0.01, ***p < 0.001. Source data are provided as a Source Data file