Table 3 Hepatic lipid content in WT and AT-1sTg mice fed control and high-carb diet

From: Acetyl-CoA flux regulates the proteome and acetyl-proteome to maintain intracellular metabolic crosstalk

 

Control diet

High-carb diet

WT

AT-1 sTg

WT

AT-1 sTg

Cytosolic acetyl-CoA (nmol/g tissue)

5.02 ± 1.83

3.19 ± 0.33*

5.70 ± 2.91

4.88 ± 2.83

Fatty acids (µmol/g tissue)

9.28 ± 2.45

6.27 ± 1.40**

15.99 ± 5.54**

6.36 ± 3.48**

Triglycerides (µmol/g tissue)

20.01 ± 7.79

6.92 ± 2.03#

34.38 ± 7.97 #

10.65 ± 4.49#*

Total cholesterol (µmol/g tissue)

3.26 ± 0.64

3.31 ± 0.42

4.17 ± 1.25

4.04 ± 0.52

  1. Hepatic lipid content of WT and AT-1 sTg mice (control diet, n = 5 per group; HCD, n = 5 per group). Bold indicates difference between diet groups, non-bold indicates difference between WT and AT-1 sTg mice on the same diet. One-tailed Student’s t test. *P < 0.05; **P < 0.005; #P < 0.0005
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