Fig. 2
From: TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors
DMXAA induces a weak immune infiltrate in Spont-PyMT tumors. a The proportion of CD45+ cells in Spont-PyMT or Trans-PyMT tumors before treatment (gray circles) and at days 1 to 8 after DMXAA i.p. injection (black circles) was determined by flow cytometry after dissociation of the tumors. b The proportion of neutrophils, TAM, monocytes, and CD8+ T cells among those CD45+ cells are shown. For day 0, Spont-PyMT n = 12 and Trans-PyMT n = 30 mice, for day 1 Spont-PyMT n = 6 and Trans-PyMT n = 12, for day 4 Spont-PyMT n = 9 and Trans-PyMT n = 24 and for day 8 Spont-PyMT n = 7 and Trans-PyMT n = 10. The data are from four to seven independent experiments for each group of mice. Results are expressed as mean ± SEM. Tukey’s multiple comparison test. *p < 0.05; **p < 0.01; ***p < 0.001. Source data are provided as a Source Data file
