Fig. 4 | Nature Communications

Fig. 4

From: Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer

Fig. 4

Integration-promoted DNA sliding observed by cryo-EM. a On the left, slabbed view of the isolated D02 NCP. Histone H3 L1 element is highlighted with a blue ball. On the right, DNA looping required for retroviral integration causes a shift in the DNA register, which extends from SHL 7 to 2. Histone H3 L1 element prevents downstream DNA sliding. b Schematic representation of integration-induced NCP remodelling

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