Fig. 7 | Nature Communications

Fig. 7

From: Biomechanical signaling within the developing zebrafish heart attunes endocardial growth to myocardial chamber dimensions

Fig. 7

Model of intra-organ communication within the developing zebrafish heart. Myocardial chamber expansion causes increased tensile forces within the endocardial cell junctions which are transmitted by Cadherin-5. This in tune causes the nuclear translocation of the Hippo signaling transcription factor Yap1 activating cell proliferation within endocardial cells

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