Fig. 9 | Nature Communications

Fig. 9

From: Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure

Fig. 9

Changes in expression structural and functional genes after 5% CSE exposure for 1 week. a, b Double immunofluorescent staining for expression p63 (red) and Laminin alfa 5 (green) in control VF mucosa (a) and CSE VF mucosa (b). c, d Immunofluorescent staining comparing the expression of E- Cadherin (red) in control VF mucosa with slightly more intense staining in the basal cell layer (c) and CSE treated VF mucosa (d). e, f Immunofluorescent staining comparing the expression of MUC1 (green) in control VF mucosa (e) with more intense MUC1 staining in the CSE VF mucosa (f). g, h Immunofluorescent staining comparing the expression of MUC4 (green) in control VF mucosa (g) with a slightly more intense MUC4 staining in the CSE VF mucosa (h). i, j Distribution of Ki67 + VFEC and VFF in control VF mucosa (i) and CSE exposed VF mucosa (j). CSE cigarette smoke extract, wk week

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