Fig. 2
From: MLL1 is required for PAX7 expression and satellite cell self-renewal in mice
Loss of MLL1 decreases H3K4me3 marks at Myf5 and Pax7 loci in Mll1 cKO myoblasts. a Location of primer sets relative to Myf5 transcription start site (TSS) for ChIP-qPCR analysis of Myf5 promoter. b Location of primer sets relative to Pax7 TSS and its downstream region for ChIP-qPCR analysis of Pax7 promoter. c ChIP-qPCR analysis of H3K4me3 enrichment, normalized to total H3, at Myf5 and Pax7 loci in control and Mll1 cKO myoblasts, obtained after 4OHT-treated or EtOH-treated RosaCE/+:Mll1fl/fl myoblasts (n = 5 independent experiments). IgH enhancer region is used as a negative control. Percent change in H3K4me3 enrichment between control and Mll1 cKO myoblasts is indicated for each region
