Table 2 PTEN plus ARID4B and PIK3CA increased predictive power for prostate cancer recurrence in multivariate Cox regression analysis using the human prostate cancer dataset GSE40272 (n = 89)

From: Identification of the PTEN-ARID4B-PI3K pathway reveals the dependency on ARID4B by PTEN-deficient prostate cancer

Multivariate Cox

P value

HR

95% CI

ARID4B

0.059

2.34

0.97–5.64

PIK3CA

0.790

0.9

0.4–2.01

PTEN

0.379

1.44

0.64–3.28

ARID4B + PIK3CA

0.05

2.41

1–5.82

PTEN + ARID4B

0.010

4.11

1.4–12.06

PTEN + PIK3CA

0.72

1.16

0.51–2.62

PTEN + ARID4B + PIK3CA

0.006

4.58

1.56–13.42

  1. Statistical analysis: log-rank test
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