Fig. 4
From: Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas
Characteristics of hemispheric glioma in infants. a Histological grade and molecular alterations in Group 1 Hemispheric RTK and Group 2 Hemispheric RAS/MAPK infant gliomas. b Overall survival (OS) of infants according to glioma subgroups, p value calculated using the log-rank test. c Survival of infants with hemispheric gliomas with respect to patient ALK, ROS1, and NTRK status, p value calculated using the log-rank test. d Hematoxylin and eosin (H&E) staining of an infant high grade glioma at diagnosis and second surgery post-chemotherapy, showing a maturing phenotype characterized by lower grade histology. Images are taken at the stated magnification, scale bar = 100 μm for x20, 200 μm for ×4. HGG: high-grade glioma, LGG: low-grade glioma
