Fig. 3

A release-insensitive mechanism of short-term depression is controlled by [K+]-dependent gating. a, b Mean profiles of [DA]o elicited by single or paired electrical pulses in 1.25 mM (light grey), 5 mM (dark grey) and 7.5 mM [K+]o (black) in CPu (a, n = 3) and NAc (b, n = 3). c, d Mean P2/P1 (± SEM) vs IPIs in 1.25 mM (light grey), 5 mM (dark grey) and 7.5 mM [K+]o (black) in CPu (c) and NAc (d). e Mean P2/P1 vs mean peak 1p [DA]o in 1.25 mM (light grey), 5 mM (dark grey) and 7.5 mM (black) [K+]o in CPu (filled) and NAc (open circles) at 10 ms IPI (left) and 100 ms IPI (right). Two-way ANOVA with Bonferroni’s test for post hoc comparisons; *P < 0.05, ***P < 0.001. Error bars are ± SEM. Source data are provided as a Source Data file