Fig. 4

K+-dependent gating of short-term depression requires axonal Kv channels. a, e Mean profiles of [DA]o transients in CPu elicited by single or paired electrical pulses in control conditions (black) or with 100 µM 4-AP (grey) in CPu (a, n = 4) and NAc (e, n = 3). Data are normalised to peak 1p-evoked [DA]o (P1) in control conditions (vertical scale bars). b, f Mean 1p [DA]o (± SEM), and individual data points in CPu in 1 mM and 5 mM [K+]o in control conditions (black/grey) or 4-AP (reds) in CPu (b) or in NAc (f). c, g Mean P2/P1 in CPu vs IPI in 5 mM (black) and 1 mM (grey) [K+]o in control conditions (left) and 4-AP (right) in CPu (c) and in NAc (g). d, h Mean P2/P1 in CPu at 25 ms IPI in 1 mM and 5 mM [K+]o in control conditions or 4-AP in CPu (d) and in NAc (h). d Asterisks indicate interaction between [K+]o and 4-AP. Two-way ANOVA with Bonferroni’s test for post hoc comparisons; *P < 0.05, **P < 0.01. Error bars are ± SEM. Source data are provided as a Source Data file