Fig. 7 | Nature Communications

Fig. 7

From: Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter

Fig. 7

DATs limits release-dependence of short-term plasticity in CPu. a Mean profiles of [DA]o transients (± SEM, vertical scale normalised to 1p in 2.4 mM [Ca2+]o) (n = 4) elicited by single or paired electrical pulses in 2.4 mM (upper) and 1.2 mM [Ca2+]o (lower) in control conditions (black) or 5 µM cocaine (blue). b, c Mean P2/P1 vs IPI in 1.2 mM (light) and 2.4 mM [Ca2+]o (dark) in control conditions (b) or cocaine (c). d Mean P2/P1 in 1.2 mM and 2.4 mM [Ca2+]o in control conditions (black-grey) or cocaine (blue) at 25 ms IPI (left) or 40 ms IPI (right). Two-way ANOVA with Bonferroni’s test for post hoc comparisons; *P< 0.05, **P< 0.01, ***P< 0.001. Source data are provided as a Source Data file

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