Fig. 3
From: Non-enzymatic roles of human RAD51 at stalled replication forks
Replication tract shortening after HU treatment requires DNA2 and FBH1 activity. a DNA2 depletion prevents replication tract shortening after treatment with 4 mM HU for 8 h. Box plot represents the IdU/CldU ratio of tracts measured in U2OS cells after the indicated treatment. b FBH1depletion prevents replication tract shortening after treatment with 4 mM HU for 8 h. Data represent at least 100 replication tracts from two independent experiments. Box plot represents the IdU/CldU ratio of tracts measured in U2OS cells after the indicated treatment. Lines represent the median for each set of measurements. Boxes represent 25th and 75th quartiles with Tukey whiskers (see methods for details). Values are presented as mean ± SD. Statistical significance was determined using Mann–Whitney test. Source data are provided as a source data file
