Fig. 4
From: Glycan-mediated enhancement of reovirus receptor binding
Probing reovirus binding to JAM-A on model surfaces. a Binding of single virions (T3SA+ or T3SA−) to JAM-A probed on a model surface. b DFS plot showing the force required to separate T3SA+ (upper panel) or T3SA− (lower panel) virions from JAM-A and fitted with the BE model. Error bars indicate s.d. of the mean value. For all experiments, data are representative of at least n = 5 independent experiments. c Box plot of the binding frequency of reovirus to JAM-A model surface. T3SA+ interactions are shown in grey, T3SA− in white, and hatched boxes represent injection of 10 µg/mL JAM-A antibody (Ab). The horizontal line within the box indicates the median, boundaries of the box indicate the 25th and 75th percentile, and the whiskers indicate the highest and lowest values of the results. The square in the box indicates the mean. ns, P > 0.05; ****P < 0.0001; determined by two-sample t-test in Origin. Source data are provided as a Source Data file
