Table 1 Comparision of liver lysate XOR activity

From: Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth

 

XO ki vs. wild-type

XDH ki vs. wild-type

 

Activity (nmol/min/mg protein)

Activity (nmol/min/mg protein)

 

NAD (−)

NAD (+)

NAD (−)

NAD (+)

Wild-type litter mate

0.64 ± 0.05

3.97 ± 0.11

0.53 ± 0.06

4.10 ± 0.31

Mutant

1.22 ± 0.14

1.19 ± 0.15

0.66 ± 0.14

4.11 ± 0.41

  1. NAD (−), rate of urate formation for xanthine-O2 turnover
  2. NAD (+), rate of urate formation for xanthine-NAD+ and xanthine-O2
  3. Sample number of XO ki mice, wild type litter mate of XO ki, XDH ki mice, and wild type litter mate of XDH ki were 7, 5, 6, and 6, respectively. Activities indicated by mean ± SEM values
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