Table 1 Calorimetry features of adult Tmem127 knockout mice

From: The tumor suppressor TMEM127 regulates insulin sensitivity in a tissue-specific manner

Measurement

WT

KO

Student’s t test

ANCOVA

RMR (mL/hr/glbm)

1.636 ± 0.07 (n = 7)

1.973 ± 0.128 (n = 6)

P = 0.05

P = 0.09

Food consumption (kcal/mouse/day)

13.97 ± 1.5 (n = 16)

12.16 ± 0.65 (n = 32)

P = 0.31

P = 0.3

Locomotor activity (beam breaks, total count)

29,206 ± 2399 (n = 5)

20,359 ± 1315 (n = 5)

P = 0.01

P = 0.03

RQ

0.948 ± 0.014 (n = 7)

0.961 ± 0.006 (n = 6)

P = 0.43

P = 0.6

  1. Data are presented as mean ± standard error of the means (SEM). Number of mice used in each experiment (n) is indicated. Measurements obtained from males, ages 9–17 mo under a regular diet
  2. RMR resting metabolic rate, calculated from the five lowest values of the adjusted oxygen consumption (VO2), measured in mL/hr/glbm (grams of lean body mass), RQ respiratory quotient, calculated by dividing carbon dioxide consumption (VCO2) by VO2 (RQ, VCO2/VO2), ANCOVA analysis of covariance
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