Fig. 1

Associations of Chromosome Y signals with old age and a total of 50 genetic determinants in mLOY. a An association between mLOY and age at blood collection is indicated. We do not show outliers in the figure. Bars indicate the most extreme data points which are no more than 1.5 times interquartile ranges from the boxes. b Polygenetic architecture in mLOY. Mean chi-square statistics and LD scores in 100 bins of Hapmap project variants in mLOY are indicated. Bins are made according to LD scores to contain almost equal number of variants in each bin. c Manhattan plot of mLOY in this study. Green and red colors indicate previously reported and unreported regions, respectively. Only P-values >1.0 × 10⁻³⁰ are shown