Fig. 7 | Nature Communications

Fig. 7

From: Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy

Fig. 7

Metastasis prevention via SMPAI-induced long-term immune effects. a Schematic illustration for SMPAI-mediated inhibition of tumor metastasis. b Representative photographs of lung tissues with tumor metastasis. c H&E staining of lung tissues collected on day 51 (scale bars: 100 μm). d Quantification of pulmonary metastasis nodules in different groups of 4T1 tumor-bearing BALB/c mice (n = 5 biologically independent samples). e, f Proportions of TEM cells in the spleens and lymph nodes (gated on CD3+ CD8+ T cells) examined after 1 day post intravenous infusion of the 4T1 cells. Data are presented as mean ± SEM (n = 3 biologically independent samples). The comparison of two groups was followed by unpaired Student’s t-test (two-tailed). *P < 0.05 and **P < 0.01

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