Table 1 Summary of sequences used to investigate the emergence of fluoroquinolone-resistant Shigella sonnei

From: Dissecting the molecular evolution of fluoroquinolone-resistant Shigella sonnei

Country

Number of sequences

In CenAsiaIII clade

CIP resistant isolates

Study or Institute of origin

Patient group

Region of recent travel history (N)

Sequencing platform

CIP susceptibility test

Bhutan

71

71

71

Diarrhoeal disease surveillance in JDWNRH, Thimphu, Bhutan (AFRIMS)

Hospitalised children <5 years old

NA

Illumina HiSeq 2000

Disk diffusion/E-test

Vietnam

24

22 (−2 poor sequencing quality)

22

Diarrhoeal disease surveillance in HCMC, Vietnam

Hospitalised children <5 years old

NA

Illumina MiSeq

Disk diffusion

Thailand

8

8

1

Cross-sectional study of S. sonnei diversity in Southeast Asia (AFRIMS)

Hospitalised children <5 years old

NA

Illumina HiSeq 2000

Disk diffusion

Cambodia

1

1

1

Cross-sectional study of S. sonnei diversity in Southeast Asia (AFRIMS)

Hospitalised children <5 years old

NA

Illumina HiSeq 2000

Disk diffusion

Ireland

20

20

16

National Salmonella, Shigella and L. monocytogenes Reference Laboratory, Galway, Ireland

Primarily patients with recent travel history

South Asia (9), Africa (1), Europe (1), No travel (5), Unknown (4)

Illumina HiSeq 2000

Broth microdilution

Australia

85

77

46

Microbiological Diagnostic Unit Public Health Laboratory, Melbourne, Australia

Primarily patients with recent travel history

Africa (2), America (1), Southeast Asia (12), Middle East (2), Oceania (1), South Asia (60), Unknown (4)

Illumina NextSeq

Agar dilution

France

97

95

72

French National Reference Centre for E. coli, Shigella, and Salmonella, Paris, France

Primarily patients with recent travel history

Africa (4) America (1) Southeast Asia (4) South Asia (88)

Illumina HiSeq 2000

Disk diffusion

England

91

90

82

Gastrointestinal Bacteria Reference Unit, Public Health England, London, UK

Primarily patients with recent travel history

Africa (3), East Asia (1), Europe (13), Middle East (1), South Asia (73)

Illumina HiSeq 2000

Disk diffusion

Global references

14

11

0

NA

NA

NA

Illumina HiSeq 2000

NA

Total

411

395

311

     
  1. CIP ciprofloxacin, JDWNRH Jigme Dorji Wangchuk National Reference Hospital, AFRIMS Armed Forces Research Institute of Medical Sciences, HCMC Ho Chi Minh City