Table 1 General characteristics of the Rotterdam Study Microbiome cohort

From: Intestinal microbiome composition and its relation to joint pain and inflammation

Rotterdam Study Microbiome

Females

Males

Total

Cohort participants

821

606

1.427

Age (years)

56.8 (5.9)

56.9 (5.9)

56.9 (5.9)

BMI (kg/m2)

27.4 (4.9)

27.6 (4.0)

27.5 (4.5)

Alcohol (g/day)

1.3 (2.7)

1.3 (2.3)

1.3 (2.6)

Smoking (y/n)

98 smokers/721 non smokers

97 smokers/507 non smokers

195 current smokers

PPI (y/n)

182 users/638 non-users

114 users/492 non-users

296 current PPI users

NSAIDs (y/n)

127 users/693 non-users

51 users/555 non-users

178 current NSAID users

Knee phenotypes

Knee OA (y/n)

84 cases/456 controls

40 cases/361 controls

124 cases/817 controls

KLSum score

1.0 (1.4)

0.7 (1.2)

0.8 (1.3)

WOMAC-Pain score

1.2 (2.6)

0.6 (1.9)

0.9 (2.3)

WOMAC-Pain score > 0

206

79

285

α-diversity metrics

Shannon Index

4.0 (4.1)

4.0 (4.0)

4.0 (0.5)

Inverse Simpson Index

26.0 (12.1)

25.5 (12.2)

25.8 (12.2)

  1. Depicted are the mean and the SD (standard deviation) in parenthesis
  2. PPI oral use of proton pump inhibitors, NSAIDs oral use of non-steroidal anti-inflammatory drugs, OA osteoarthritis, WOMAC Western Ontario and McMaster Osteoarthritis Index