Table 1 General characteristics of the Rotterdam Study Microbiome cohort
From: Intestinal microbiome composition and its relation to joint pain and inflammation
Rotterdam Study Microbiome | Females | Males | Total |
|---|---|---|---|
Cohort participants | 821 | 606 | 1.427 |
Age (years) | 56.8 (5.9) | 56.9 (5.9) | 56.9 (5.9) |
BMI (kg/m2) | 27.4 (4.9) | 27.6 (4.0) | 27.5 (4.5) |
Alcohol (g/day) | 1.3 (2.7) | 1.3 (2.3) | 1.3 (2.6) |
Smoking (y/n) | 98 smokers/721 non smokers | 97 smokers/507 non smokers | 195 current smokers |
PPI (y/n) | 182 users/638 non-users | 114 users/492 non-users | 296 current PPI users |
NSAIDs (y/n) | 127 users/693 non-users | 51 users/555 non-users | 178 current NSAID users |
Knee phenotypes | |||
Knee OA (y/n) | 84 cases/456 controls | 40 cases/361 controls | 124 cases/817 controls |
KLSum score | 1.0 (1.4) | 0.7 (1.2) | 0.8 (1.3) |
WOMAC-Pain score | 1.2 (2.6) | 0.6 (1.9) | 0.9 (2.3) |
WOMAC-Pain score > 0 | 206 | 79 | 285 |
α-diversity metrics | |||
Shannon Index | 4.0 (4.1) | 4.0 (4.0) | 4.0 (0.5) |
Inverse Simpson Index | 26.0 (12.1) | 25.5 (12.2) | 25.8 (12.2) |