Table 2 Results of multivariate linear regression analysis of gut microbiome relative abundancies and knee WOMAC-pain scores, in the Rotterdam Study, LifeLines-DEEP
From: Intestinal microbiome composition and its relation to joint pain and inflammation
Taxonomy | % | RS N | RS CoE | RS SE | RS P-value | RS FDR | LLD N | LLD CoE | LLD SE | LLD P-value | Meta N | Meta P-value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Class Bacilli | 27.3% | 1419 | 6.1 × 10−03 | 1.0 × 10−03 | 9.1 × 10−09 | 1.0 × 10−06 | 867 | 5.4  × 10−03 | 1.3  ×  10−03 | 3.6 × 10−05 | 2286 | 1.1 × 10−12 |
Order Lactobacillales | 100% | 1417 | 6.1 × 10−03 | 1.1  × 10−03 | 7.6  × 10−09 | 1.0 × 10−06 | 864 | 4.9 × 10−03 | 1.3 ×  10−03 | 2.4 × 10−04 | 2281 | 8.3 × 10−12 |
Family Streptococcaceae | 79.6% | 1402 | 4.9 × 10−03 | 9.3  × 10−04 | 1.5 ×  10−07 | 8.7 × 10−06 | 863 | 2.9 × 10−03 | 1.3  × 10−03 | 2.3 × 10−02 | 2265 | 2.1 × 10−08 |
Genus Streptococcus | 98.7% | 1396 | 5.0  × 10−03 | 9.3  × 10−04 | 7.3 × 10−08 | 5.6 × 10−06 | 860 | 3.3 × 10−03 | 1.6 × 10−03 | 3.7  × 10−02 | 2256 | 1.3  × 10−08 |
