Table 3 Scope of organoboronic acids and alkenes in oxidative Heck arylation

From: Nickel-catalyzed intermolecular oxidative Heck arylation driven by transfer hydrogenation

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  1. Reaction conditions: Ni(cod)2 (10 mol%), ligand (20 mol%), CsOPiv (1.5 equiv), alkene (0.2 mmol), arylboronic acid (0.4 mmol), t-AmylOH (1 mL), 70 °C, 48 h. Values correspond to isolated yields. In cases where the E/Z ratio is not specified, only the E-alkene product was observed
  2. aThe values parentheses represent the isolated yield using Ni(cod)2 (5 mol%) and ligand (10 mol%)
  3. bPMe3 (20 mol%), 120 °C
  4. ct-AmylOH (1.5 mL)
  5. dZ/E ratios were determined by 1H NMR
  6. eThe Z/E ratio of substrate 1i was 91:9
  7. fNi(cod)2 (20 mol%), PnBu3 (40 mol%), 120 °C, 72 h
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