Fig. 1 | Nature Communications

Fig. 1

From: Renal clearable nanochelators for iron overload therapy

Fig. 1

Renal clearable nanochelators to treat secondary hemochromatosis: a Nanochelators are composed of multiple DFO moieties conjugated on renal clearable EPL backbone to minimize nonspecific uptake into immune-related organs, while efficiently capturing plasma iron and being cleared exclusively by the kidneys. b Synthetic scheme of renal clearable DFO-NPs. m represents the number of DFO moieties conjugated on EPL. NIR fluorescent ZW800-1C (green color) was conjugated to track the fate of nanochelators in the body

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