Fig. 6
From: Transplanted interneurons improve memory precision after traumatic brain injury
Silencing transplanted interneurons increases fear memory generalization. a Schematic of the contextual fear conditioning protocol for DREADD-mediated cell silencing. b, c Quantification of freezing behavior in contexts A and B during the replication experiment and after Compound 21 administration. Replication: **P = 0.005, control vs TBI; **P = 0.006, TBI vs TBI-MGE-hM4Di; one-way ANOVA with Bonferroni post hoc test. Compound 21: **P = 0.01, control vs TBI; *P = 0.03, control vs TBI-MGE-hM4Di; one-way ANOVA with Bonferroni post hoc test. n = 8 control mice, 7 TBI mice, 5 TBI-MGE-hM4Di mice. d–f Quantification of freezing in contexts A and B for each individual mouse during the replication experiment (Rep) and after Compound 21 (C21) administration. **P = 0.009, TBI-MGE-hM4Di two-tailed paired t-test. See Supplementary Data 1 for statistical analyses. Error bars, s.e.m. Source data are provided as a Source Data file
