Fig. 2
Frequency of X-chromosome mutation was greater in females than males for the 12 disparity cancers. a The scheme shows our strategy for bioinformatic data analyses of exome mutations, their expression and overall mRNA content analyses in TCGA data sets; with corresponding figure identity listed on the right. On a per patient basis, (b) the number of exome mutations in the autosomes and X chromosomes and the (c) number of exome mutations for the X chromosome alone are presented (and importantly this collective data aligns with the individual cancers as evident in Supplementary Fig. 2a, b). Females are indicated in pink and males in blue. These are standard boxplots with the median as the centre line across the boxed-in upper and lower quartiles, with maximum and minimum values demarcated by whiskers.
