Fig. 4
Non-expressed mutation (NEM) frequencies were significant only in females, and the p53-STRING set genes were more prominent than the other X-chromosome genes. The relative incidence (x-axis: log2 ratio [F/M]) and significance [y-axis; - log10(p-value)] of NEMs was compared for all X-linked genes between females and males of the 12 disparity cancers. P53-STRING set genes are blue, others are gold. NEMs showing a significant sex difference are indicated by a triangle, and those lacking significance by a circle. The number of NEMs for each gene are indicated by a correlative, sliding scale of size.
