Fig. 5

High expression levels of negative regulators of p53 among the p53-STRING set are more frequent in wt TP53 cancers and associate with reduced survival. a Gene set enrichment analysis (GSEA) of the expression of the X-linked negative regulators of p53 compared between the disparity cancers with wt Tp53 and their matched normals. b Kaplan–Meier survival curves were generated for cancer patients with wt Tp53 tumours on the basis of the relative expression levels of the X-linked p53-negative regulators UBE2A, UPT14A and MAGE2A, respectively (top median: broken red line and bottom median: solid black line).