Table 1 Comparison of filament end occupancy by Srv2 and depolymerization rate.

From: Synergy between Cyclase-associated protein and Cofilin accelerates actin filament depolymerization by two orders of magnitude

Srv2 concentration, c (nM)

Fractional occupancy of filament ends by Srv2a

Fraction of saturating velocityb

8.3

16 ± 3%

14 ± 2%

83

66 ± 15%

62 ± 5%

  1. aCalculated from koff and kon measured in single-molecule observations of Cy5-Srv2ΔCARP on filament ends (see text and Fig. 4) as c KA / (1 + c KA), where KA = kon / koff
  2. bCalculated as c / (c + KM) using the KM value reported in Fig. 2e
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