Fig. 8 | Nature Communications

Fig. 8

From: LncRNA REG1CP promotes tumorigenesis through an enhancer complex to recruit FANCJ helicase for REG3A transcription

Fig. 8The alternative text for this image may have been generated using AI.

Schematic illustration of the function of REG1CP. REG1CP acts as a two-stage address code to facilitate REG3A transcription through assembling a long-range enhancer complex via forming an RNA–DNA triplex with the REG3A gene. DNA looping through structural folding of the REG3A DNA is proposed to facilitate the specific targeting of FANCJ to the transcriptionally active region of REG3A.

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