Fig. 1
From: Dynamic constriction and fission of endoplasmic reticulum membranes by reticulon
The genetic antagonism between Rtnl1 and atlastin in Drosophila is reflected in morphological alterations of the ER. a The histogram displays the percentage of surviving adults, expressed as the ratio of observed over expected individuals, for the indicated genotypes. n = 3 independent experiments, statistical significance: unpaired two-tailed t test, ***p < 0.001. Error bars represent SEM. b EM tomography-based 3D reconstruction of portions of the ER network from neurons of the indicated genotypes. ER elements not connected are shown in color. Scale bar 200 nm. c Representative EM images of ventral ganglion neuronal bodies of the indicated genotypes highlighting ER profiles in red. Scale bar 0.5 μm. pm plasma membrane, m mitochondria, n nucleus. d average length of ER profiles measured on thin EM sections shown in (c), n > 100 ER profiles. Statistical significance: unpaired two-tailed t test, ***p < 0.001. Error bars represent SEM. Source data are provided as a Source Data file.
