Fig. 4 | Nature Communications

Fig. 4

From: Targeting specificity of APOBEC-based cytosine base editor in human iPSCs determined by whole genome sequencing

Fig. 4

The off-target mutations are randomly distributed. a Chromosomal distribution of C:G>T:A and C:G>G:C mutations in iPSC clones that each has >500 total mutations. Error bar represents standard deviation (n = 2). Source data are provided in the Source Data file. b Numbers of mutation overlaps between iPSC clones edited at either HEK3 or RNF2 locus. The numbers of mutations include on-target mutation(s). A complete comparison of mutations among all sequenced iPSC clones is shown in Supplementary Table 4.

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