Table 1 Summary of the VHX (columns one to three) and the BPD (columns four and five) trial features.
From: Resolving the cause of recurrent Plasmodium vivax malaria probabilistically
AS | CQ | PMQ + CQ | PMQ + CQ | PMQ + DP | |
|---|---|---|---|---|---|
Number of patients, \(n\) | 224 | 222 | 198 | 329 | 326 |
Male patients (%) | 71 | 65 | 64 | 66 | 63 |
Median patient age [years] (range) | 19 (1.5–62) | 18 (1.5–62) | 18 (2–63) | 20 (1.5–61) | 20 (1.3–63) |
Median days follow-up (range) | 314 (1–393) | 364 (11–412) | 364 (0–383) | 364 (7–415) | 364 (7–685) |
Geometric mean parasites per μL at enrolment (range) | 4113 (144–47,665) | 3920 (168–44,211) | 3524 (136–62,298) | 4134 (32–59,032) | 3726 (48–381,824) |
Number of patients whose infections recurred, \({n}_{\mathrm{r}}\) (% of \(n\)) | 177 (39) | 165 (36) | 35 (8) | 47 (10) | 34 (7) |
\({n}_{\mathrm{r}}\) with one or more paired recurrence genotyped and analysed (% of \({n}_{\mathrm{r}}\)) | 11 (6) | 88 (53) | 32 (91) | 46 (98) | 31 (91) |
Number of recurrences, \({\mathrm{r}}\) | 722 | 587 | 40 | 53 | 39 |
Number of paired recurrences genotyped and analysed (% of \({\mathrm{r}}\)) | 11 (2) | 355 (60) | 34 (85) | 52 (98) | 35 (90) |
