Fig. 4: Homologs of hMYDGF.

a Phylogenetic tree color-coded by phylum and class of 87 MYDGF homologs identified by ConSurf in the UniRef90 database using the amino acid sequence of hMYDGF lacking its signal sequence (star) as the query. b Protein sequence alignment of MYDGF homologs from each of the classes in a with hMYDGF secondary structure displayed underneath. Asterisks represent highly conserved residues among all 236 UniProt90 MYDGF sequences identified by BLAST (black, ≥90% identity; gray, ≥85% identity).