Fig. 1: PARP1 association with DSB activators.
From: PARP1 exhibits enhanced association and catalytic efficiency with γH2A.X-nucleosome
a Domain structure of the 1024 amino acid PARP1 and corresponding N-terminal half truncation construct (NPARP1). b Kinetic parameters for NPARP1 and PARP1 binding to naked DNA, NCP and nucleosomal substrates measured by SPR (eight samples, left; mean ± s.d., n = 2 independent experiments) and BLI (four samples, right; mean ± s.d., n = 3, 2, 3, 2 independent experiments). Source data are provided as a Source Data file.
