Fig. 2: Structures of NCP composed of H2A and the H2A.X variant. | Nature Communications

Fig. 2: Structures of NCP composed of H2A and the H2A.X variant.

From: PARP1 exhibits enhanced association and catalytic efficiency with γH2A.X-nucleosome

Fig. 2

a Inter-nucleosomal annealing of the 4-nucleotide 3′ overhangs in the 147s-NCP structures (NCP assembled with H2A shown) yields continuous, 147 bp repeat, fibres composing the lattice. b Five NCP structures corresponding to superposition of the H2A.X-NCP, γH2A.X-NCP, H2A.X-S139E-NCP and H2A-147s-NCP models onto that of H2A-(145 bp)-NCP. a, b Histone proteins are coloured by type: H2A, yellow; H2A.X, bronze; H2B, pink; H3, purple; H4, green.

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