Fig. 6: Differential regulation of YR-initiation and YC-initiation during translation inhibition.

a Experimental design to study the response of YC-initiation and YR-initiation products during translation inhibition by cycloheximide. b A UCSC browser screenshot showing an example of levels of YR and YC components of the dual-initiation promoter gene rps13. The bar chart includes sum of all peaks. c Cumulative frequency of YR-initiation and YC-initiation of all ribosomal protein genes after cycloheximide treatment. X-axis indicates the log2 fold change of YR-initiation and YC-initiation in cycloheximide and wild type condition.