Fig. 2: Heritability of all 52 carboxylic acids by class.
From: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies
Box- and dotplots of the h2total, and h2Metabolite-hits for all 52 successfully analyzed carboxylic acids and derivatives across all metabolomics platforms by class. The left-hand side of the figure is a close-up of the −0.08 to 0.15 part of the heritability range, focusing on the h2Class-hits and h2Notclass-hits estimates. The boxes denote the 25th and 75th percentile (bottom and top of box), and median value (horizontal band inside box). The whiskers indicate the values observed within up to 1.5 times the interquartile range above and below the box. The purple, orange and green boxes denote the keto acid, hydroxyl acid and carboxylic acid classes, respectively. Supplementary Data 3 provides the estimates for each of the individual metabolites.
