Fig. 2: The output of CaSpER algorithm. | Nature Communications

Fig. 2: The output of CaSpER algorithm.

From: CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data

Fig. 2

CaSpER algorithm outputs detailed CNV event calls for all CNV and BAF scale pairs (Step 8). Large-scale, gene- and segment-based CNV events that are commonly seen in all scale pairs are reported (Step 9). For single-cell RNA sequencing studies, CaSpER infers CNV-based clonal evolution depicted as a phylogenetic tree (Step 10). Mutually exclusive and co-occurring CNV events are summarized using graph-based visualization (Step 11).

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