Fig. 7: Rab11A association with dynein motors is decreased during IAV infection. | Nature Communications

Fig. 7: Rab11A association with dynein motors is decreased during IAV infection.

From: Quantitative live cell imaging reveals influenza virus manipulation of Rab11A transport through reduced dynein association

Fig. 7

Mass spectrometry of immunoprecipitation (IP) input or α-GFP IP from A549 GFP-Rab11A cells either uninfected or infected with H1N1pdm. a Gene Ontology analysis of Rab11A-interacting cellular proteins revealed by immunoprecipitation–mass spectrometry. b Change in Rab11A-interacting proteins as a ratio of infected to mock cells. Vesicle transport-related proteins significantly altered during infection and viral polymerase proteins are highlighted. c Ratio of host proteins in IP input as a ratio of infected to mock cells. d Validation and quantification of dynein levels bound to Rab11A in mock or H1N1pdm-infected cells. Relative band intensity of dynein is noted below the western blot and molecular weight size markers indicated to the right. Source data are provided as a Source Data file.

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