Table 1 Selected genes positively correlated in expression with occurrence of upstream SV breakpoint.
Region: | 0–20 kb upstream | 20–50 kb upstream | 50–100 kb upstream | Gene body | 0–20 kb downstream | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Gene | n | t | n | t | n | t | n | t | n | t |
CDK4 | 16 | 2.39 | 27 | 8.67 | 23 | 5.94 | 13 | 1.92 | 21 | 5.93 |
ERBB2 | 13 | 3.66 | 17 | 7.99 | 34 | 11.87 | 23 | 8.55 | 15 | 2 |
MDM2 | 17 | 9.5 | 22 | 7.9 | 21 | 9.52 | 20 | 8.84 | 19 | 8.35 |
TERT | 31 | 8.08 | 9 | 2.34 | 8 | 0.73 | 10 | 7.39 | 5 | 6.81 |
CDK12 | 7 | 0.33 | 14 | 3.78 | 14 | −0.02 | 41 | 2.8 | 11 | 3.01 |
HMGA2 | 10 | 3.71 | 8 | 4.31 | 15 | 1.71 | 24 | 2.16 | 6 | −0.84 |
EGFR | 8 | 1.69 | 12 | 4.39 | 9 | 2.41 | 31 | 5.57 | 6 | 4.01 |
TBL1XR1 | 3 | 0.38 | 9 | 3.51 | 9 | 1.11 | 32 | 2.23 | 4 | 2.02 |
MYCL | 4 | 2.23 | 5 | −0.14 | 10 | 4.24 | 0 | NA | 5 | 3.05 |
CCND3 | 3 | 2.97 | 6 | 4.01 | 7 | 4.18 | 15 | 4.53 | 5 | 1.44 |
CLTC | 7 | 1.99 | 4 | 1.66 | 5 | 3.98 | 14 | 0.43 | 6 | 2.93 |
PDCD1LG2 | 3 | 3.8 | 8 | 4.02 | 4 | 0.97 | 9 | 7.81 | 6 | 5.33 |
PTPN11 | 4 | 2.83 | 3 | 3.88 | 7 | 2.59 | 7 | 1.1 | 3 | −0.61 |
SMARCE1 | 2 | NA | 6 | 4.7 | 6 | 3.29 | 6 | 0.75 | 1 | NA |
PDGFRA | 3 | 3.81 | 4 | 0.07 | 6 | 0.04 | 7 | 1.51 | 2 | NA |
NF1 | 1 | NA | 3 | 4.44 | 8 | 2.87 | 65 | −2.98 | 0 | NA |
CD274 | 3 | 3.33 | 3 | 1.64 | 6 | 1.42 | 6 | 5.27 | 4 | 5.1 |
PRKAR1A | 2 | NA | 3 | 1.3 | 3 | 3.39 | 4 | 2.29 | 1 | NA |
MYB | 5 | −0.18 | 3 | 3.58 | 0 | NA | 1 | NA | 1 | NA |
FOXL2 | 2 | NA | 3 | 5.27 | 3 | −0.48 | 0 | NA | 2 | NA |
BCL7A | 3 | 2.54 | 1 | NA | 3 | 3.38 | 7 | 1.76 | 3 | 2.86 |
SS18 | 0 | NA | 3 | 3.57 | 4 | 0.49 | 8 | 3.57 | 1 | NA |
TFE3 | 3 | 3.45 | 1 | NA | 2 | NA | 2 | NA | 0 | NA |
NKX2-1 | 1 | NA | 3 | 4.24 | 2 | NA | 0 | NA | 1 | NA |
