Table 1 Baseline characteristics of the 15 investigated myelofibrosis patients.
From: Single-cell analysis based dissection of clonality in myelofibrosis
Patient | Age at baseline | Sex | Diagnosis | Disease progression | Karyotype at baseline WES | Response to ruxolitinib | alive/dead | Cause of death |
|---|---|---|---|---|---|---|---|---|
MPN01 | 73 | Male | PMF | No | 46, XY | Durable response | Alive | n.a. |
MPN02 | 64 | Male | PMF | Yes | 46,XY,del(11)(q13-14q23) | Progression to AML | Dead | AML |
MPN03 | 65 | Female | Post-PV-MF | No | 46,XX | Durable response | Alive | n.a. |
MPN04 | 70 | Female | Post-ET-MF | Yes | 46, XX, del (5)(q23q32) | Progression to AML | Dead | AML |
MPN05 | 70 | Male | PMF | No | 46, XY | Durable response | Alive | n.a. |
MPN06 | 75 | Female | PMF | No | 46,XX | Durable response | Alive | n.a. |
MPN07 | 59 | Female | Post-ET-MF | No | 46,XX | Durable response | Alive | n.a. |
MPN08 | 72 | Male | PMF | No | 46,XY | Durable response | Alive | n.a. |
MPN09 | 48 | Female | Post-PV-MF | No | 46,XX | Molecular remission | Alive | n.a. |
MPN10 | 76 | Female | PMF | No | 46,XX | Durable response | Dead | Heart failure |
MPN11 | 75 | Female | Post-PV-MF | No | 46,XX | Durable response | Dead | Multi-organ failure following complicated colon cancer operation |
MPN16 | 67 | Male | PMF | No | 46,XY | Durable response | Alive | n.a. |
MPN17 | 47 | Female | Post-PV-MF | No | 46,XX | Durable response | Alive | n.a. |
MPN18 | 64 | Male | PMF | Yes | 46,XY | Disease acceleration | Dead | Sepsis in disease progression |
MPN19 | 54 | Male | Post-PV-MF | No | 46,XY | Molecular remission | Alive | n.a. |
