Fig. 1: Expression in SSB01 in hospite compared to in culture.

a Volcano plot of relative abundances of individual transcripts. x-axis, fold-changes; y-axis, adjusted p-values based on Benjamini-Hochberg correction; red and blue, transcripts more abundant in hospite and in culture, respectively. Both axes use log scales. The horizontal line indicates adjusted p-values = 0.001, the cutoff used for considering differences to be significant (see text). b The GO categories enriched (based on hypergeometric p-value < 0.1) in the transcripts showing significant differences in abundance. The p-value for the enrichment of each category is shown (x-axis), as are the total numbers of transcripts in that category that showed significant differences (adjusted p-value < 0.001; fold-change > 2) in expression and the percentages that were more abundant in hospite (pink) or in culture (blue). c Heat-map showing the log₂ fold-changes (Log₂FC, in hospite relative to in culture) of transcripts encoding putative nitrate, ammonium, adenine/guanine (NUP), and urea (URT) transporters and a putative nitrate reductase (NIT).