Fig. 8: Model for the role of the NPC in the repair of fork stalled at telomeres.
From: The nuclear pore complex prevents sister chromatid recombination during replicative senescence
Replication forks stalled at telomeres relocalize to the NPC and are mainly repaired by a conservative pathway that allows replication to resume (left). When this pathway fails, the stalled forks engage in error-prone Rad51-dependent SCR that maintain a telomere length compatible with continuous proliferation.
