Fig. 1: Regional mean [11C]UCB-J distribution volume (VT) by group. | Nature Communications

Fig. 1: Regional mean [11C]UCB-J distribution volume (VT) by group.

From: Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

Fig. 1

Grey bars depict regional mean VT in the healthy volunteer (HV) group, and triangles represent individual HV VT (n = 18). Hollow bars depict mean VT in the schizophrenia (SCZ) group, and circles indicate individual SCZ patient VT (n = 18). p Values reported here are FDR-adjusted p values. [11C]UCB-J VT was significantly reduced with large effect sizes (Cohen’s d > 0.8) in the SCZ compared to the HV group in the frontal cortex and anterior cingulate cortex (ACC). [11C]UCB-J VT was not significantly altered in the hippocampus. Error bars indicate standard error of the mean.

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