Fig. 8: A model for Gram-negative strain CF6-2 preying on Gram-positive marine bacteria for nutrients with the secreted protease pseudoalterin as a weapon.
From: A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria
Strain CF6-2 lyses Gram-positive bacterial cells by secreting the metalloprotease pseudoalterin to degrade the PG in Gram-positive bacterial cell wall, which leads to the collapse of the cell wall and subsequent lysis of the cell. Then, strain CF6-2 utilizes the d/l-amino acids and the oligopeptides released from PG degradation and the substances from the inside cell to thrive. In the meantime, the released glycine and glycine-enriching oligopeptides from the degradation of Gram-positive bacterial PG induce the synthesis of pseudoalterin in strain CF6-2, and then the synthesized pseudoalterin is secreted through the T2SS of strain CF6-2.
